Jayson Werth? OK this is very interesting.
On one hand - this barely matters. As counter intuitive as it may seem the order of your lineup isn't as make or break as you would think it is. Even if you were an idiot and set the exact worst lineup out everyday, something like Pudge, Pitcher, etc. etc. it wouldn't kill your team. Oh you'll lose a few more games, but it wouldn't be like 20. It'd be more like 5, maybe 10. You might see a bigger difference because of luck in 1-run games. (I can point you to some analyses if you like - who doesn't love Markov Chains? Probably the people he locked up in them... ha! Where's my ALF picture?)
And that's comparing your worst lineup to your best. The normal lineup - scrappy fast guy, good BA no power, best hitter maybe, or else best hitter here (usually the guy with more power between the two), decent hitter with power, last guy you have with power left, dregs... - is only going to be a win or two different from the "best" lineup. There are a ton of things that can effect a season a game or two. In other words, what's been used for 100 or so years really is good enough.
On the other hand, you might as well get every win that you can and going with a strategy that puts your high OBP guys up first is a step toward optimizing runs. Werth is a high OBP guy and batting him 2nd is a ballsy move. A GOOD ballsy move. The Nats should get more runs out of it. Sure he might drive in fewer runs, but not that much fewer since some of that loss of people to drive in will be mitigated by the increase in at bats he should see. At the same time Werth should also SCORE more runs batting second. I don't love it, but I do like it.
Two things though:
(1) I wonder how long this will actually last. Generally new and different ideas in baseball only last as long as the team is successful and the Nats don't have the talent to be that successful. It's the culture. It's fine to fail with old ideas. Hundreds of teams have done it before. You're just one of us. But fail with something new, even if it should be better in the long run, you are screwed. Who do you think you are? You think you're smarter than John McGraw? That you're better than Stengel?
(2) What happens to Desmond? I've said before I think he needs to be in a position where he sees a lot of fastballs to succeed. If the Nats truly are concerned with OBP then he can't bat first so that puts him....6th protected by Ramos or Espinosa? I'm not putting money in Desmond futures if this is the case